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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence based on a news release by them on 10-12-2010.

Using two separate drugs to shed weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err to the side of caution and let the FDA do its job and demand some study be done so that the public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies come in business to earn money and that they would say almost anything to keep people on their own medications.

Researchers found out that participants using this drug for any year, dropped a few pounds within 4 weeks and have kept the load off throughout the 56 weeks from the study. Contrave is often a combination of the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs which can be made up of multiple active ingredient, that might make them more potent and safer.

Combo-pilling may be the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular is the fact that since right now there are not any long term prescription weightloss pills that have been licensed by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be authorized by the FDA.

Seizures are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug could also raise blood pressure levels and pulse rate, and mustn't be used in those with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high blood pressure, along with by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients for the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.


The most common adverse reactions reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.
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